DONOR SELECTION: IMMUNOGENETICS AND HISTOCOMPATIBILITY

Histocompatibility and immunogenetics in cord blood transplantation.

This review of the immunogenetics of cord blood transplantation attempts to highlight the connections between classical studies and conclusions of the tissue transplantation field as a scholarly endeavor, exemplified by the work of Professor Hoecker, with the motivations and some recent and key results of clinical cord blood transplantation. The authors review the evolution of understanding of ...

Immunogenetics and the major histocompatibility complex.

The poultry immune system is a complex system involving many different cell types and soluble factors that must act in concert to give rise to an effective response to pathogenic challenge. The complexity of the immune system allows the opportunity for genetic regulation at many different levels. Cellular communication in the immune response, the production of soluble factors, and the rate of d...

Immunogenetics Human immunogenetics Editorial overview

Charles Larsen trained as a protein chemist and has studied the biophysics of viral membrane fusion. His current interest is the cellular immunology and genetics of the human nonresponse to hepatitis B vaccine. This interest has broadened to include the relationship between MHC genetic structure and autoimmune phenomena. Abbreviations CEH conserved extended haplotype KIR killer immunoglobulin-l...

Immunogenetics and infectious diseases: special reference to the mayor histocompatibility complex.

Many studies have tried to identify genetic markers for infectious diseases, some of them have focused on human leukocyte antigens (HLA). The products of HLA genes interact with surface-specific receptors of T lymphocytes, resulting in activation of the host's immune response. Association of bacterial, viral, parasitic and fungal infections with the host's HLA has been widely investigated. The ...

Selection of Donor and Recipients